K-cadherin Polyclonal Antibody
- 货号：YT5111
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Mouse;Rat
- 免疫原：
- Synthesized peptide derived from K-cadherin . at AA range: 180-260
- 特异性：
- K-cadherin Polyclonal Antibody detects endogenous levels of K-cadherin protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- CDH6;Cadherin-6;Kidney cadherin;K-cadherin
- 背景：
- This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011],
- 功能：
- function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.,
- 细胞定位：
- Cell membrane; Single-pass type I membrane protein.
- 组织表达：
- Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
- Western Blot analysis of BT474, A549, SHSY5Y, 293 cells using K-cadherin Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
