K-cadherin Polyclonal Antibody

    • 货号:YT5111
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • K-cadherin
      • 基因名称:
      • CDH6
      • 蛋白名称:
      • Cadherin-6
      • Human Gene Id:
      • 1004
      • Human Swiss Prot No:
      • P55285
      • Mouse Swiss Prot No:
      • P97326
      • 免疫原:
      • Synthesized peptide derived from K-cadherin . at AA range: 180-260
      • 特异性:
      • K-cadherin Polyclonal Antibody detects endogenous levels of K-cadherin protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • CDH6;Cadherin-6;Kidney cadherin;K-cadherin
      • 实测条带:
      • 88kD
      • 背景:
      • This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011],
      • 功能:
      • function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.,
      • 细胞定位:
      • Cell membrane; Single-pass type I membrane protein.
      • 组织表达:
      • Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
      • 产品图片
      • Western Blot analysis of BT474, A549, SHSY5Y, 293 cells using K-cadherin Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000