β-1,4-Gal-T5 Polyclonal Antibody
- 货号：YT5010
- 应用：WB;ELISA
- 种属：Human;Mouse
- 简介：
- >>Mucin type O-glycan biosynthesis;>>Sphingolipid metabolism;>>Metabolic pathways
- 蛋白名称：
- Beta-1,4-galactosyltransferase 5
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human B4GALT5. AA range:321-370
- 特异性：
- β-1,4-Gal-T5 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T5 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- B4GALT5;Beta-1;4-galactosyltransferase 5;Beta-1,4-GalTase 5;Beta4Gal-T5;b4Gal-T5;Beta-1,4-GalT II;UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5;UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5
- 背景：
- This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed
- 功能：
- cofactor:Manganese.,function:Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.,online information:Beta-1,4-galactosyltransferase 5,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 7 family.,subcellular location:Trans cisternae of Golgi stack.,tissue specificity:Ubiquitously expressed.,
- 细胞定位：
- Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Golgi apparatus . Trans cisternae of Golgi stack. .
- 组织表达：
- Ubiquitously expressed.
- Western Blot analysis of various cells using β-1,4-Gal-T5 Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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- Western Blot analysis of 293 cells using β-1,4-Gal-T5 Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
