• 靶点：
• ZIS

• 基因名称：
• ZRANB2

• 蛋白名称：
• Zinc finger Ran-binding domain-containing protein 2

• Human Gene Id：
• 9406

• Human Swiss Prot No：
• O95218

• Mouse Gene Id：
• 53861

• Mouse Swiss Prot No：
• Q9R020

• Rat Gene Id：
• 58821

• Rat Swiss Prot No：
• O35986

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human ZNF265. AA range:106-155

• 特异性：
• ZIS Polyclonal Antibody detects endogenous levels of ZIS protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• ZRANB2;ZIS;ZNF265;Zinc finger Ran-binding domain-containing protein 2;Zinc finger protein 265;Zinc finger; splicing

• 实测条带：
• 34kD

• 背景：
• domain:The RanBP2-type zinc fingers mediate binding to RNA.,function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.,PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.,sequence caution:Intron retention.,similarity:Belongs to the ZRANB2 family.,similarity:Contains 2 RanBP2-type zinc fingers.,subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,

• 功能：
• domain:The RanBP2-type zinc fingers mediate binding to RNA.,function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.,PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.,sequence caution:Intron retention.,similarity:Belongs to the ZRANB2 family.,similarity:Contains 2 RanBP2-type zinc fingers.,subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Brain,Epithelium,Fetal brain,Fetal kidney,Liver,Skin,Testis,Uterus,

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