• 靶点：
• ZIP7

• 简介：
• >>Alzheimer disease;>>Parkinson disease

• 基因名称：
• SLC39A7

• 蛋白名称：
• Zinc transporter SLC39A7

• Human Gene Id：
• 7922

• Human Swiss Prot No：
• Q92504

• Mouse Gene Id：
• 14977

• Mouse Swiss Prot No：
• Q31125

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human SLC39A7. AA range:131-180

• 特异性：
• ZIP7 Polyclonal Antibody detects endogenous levels of ZIP7 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SLC39A7;HKE4;RING5;Zinc transporter SLC39A7;Histidine-rich membrane protein Ke4;Really interesting new gene 5 protein;Solute carrier family 39 member 7

• 实测条带：
• 50kD

• 背景：
• The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

• 功能：
• similarity:Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.,tissue specificity:Major expression in placenta, lung, kidney and pancreas.,

• 细胞定位：
• Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus, cis-Golgi network membrane ; Multi-pass membrane protein .

• 组织表达：
• Widely expressed.

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