VPS26B Polyclonal Antibody
- 货号:YT4889
- 应用:WB;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- Vacuolar protein sorting-associated protein 26B
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280
- 特异性:
- VPS26B Polyclonal Antibody detects endogenous levels of VPS26B protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- VPS26B;Vacuolar protein sorting-associated protein 26B;Vesicle protein sorting 26B
- 背景:
- function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
- 功能:
- function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
- 细胞定位:
- Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity). .
- Western Blot analysis of LOVO cells using VPS26B Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Western blot analysis of lysates from LOVO cells, using VPS26B Antibody. The lane on the right is blocked with the synthesized peptide.