VPS26B Polyclonal Antibody

    • 货号:YT4889
    • 应用:WB;ELISA
    • 种属:Human;Mouse
      • 靶点:
      • VPS26B
      • 简介:
      • >>Endocytosis
      • 基因名称:
      • VPS26B
      • 蛋白名称:
      • Vacuolar protein sorting-associated protein 26B
      • Human Swiss Prot No:
      • Q4G0F5
      • Mouse Swiss Prot No:
      • Q8C0E2
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280
      • 特异性:
      • VPS26B Polyclonal Antibody detects endogenous levels of VPS26B protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • VPS26B;Vacuolar protein sorting-associated protein 26B;Vesicle protein sorting 26B
      • 实测条带:
      • 45kD
      • 背景:
      • function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
      • 功能:
      • function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
      • 细胞定位:
      • Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity). .
      • 组织表达:
      • Eye,Lung,Placenta,
      • 产品图片
      • Western Blot analysis of LOVO cells using VPS26B Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Western blot analysis of lysates from LOVO cells, using VPS26B Antibody. The lane on the right is blocked with the synthesized peptide.