• 靶点：
• USP24

• 基因名称：
• USP24

• 蛋白名称：
• Ubiquitin carboxyl-terminal hydrolase 24

• Human Gene Id：
• 23358

• Human Swiss Prot No：
• Q9UPU5

• Mouse Gene Id：
• 329908

• Mouse Swiss Prot No：
• B1AY13

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human USP24. AA range:21-70

• 特异性：
• USP24 Polyclonal Antibody detects endogenous levels of USP24 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• USP24;KIAA1057;Ubiquitin carboxyl-terminal hydrolase 24;Deubiquitinating enzyme 24;Ubiquitin thioesterase 24;Ubiquitin-specific-processing protease 24

• 分子量：
• 211kD

• 背景：
• Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],

• 功能：
• catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBA domain.,

• 细胞定位：
• cytoplasm,

• 组织表达：
• Brain,Epithelium,Placenta,Platelet,T-cell,

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