Troponin I-C Polyclonal Antibody
- 货号：YT4747
- 应用：WB;IHC;IF;ELISA
- 种属：Mouse;Rat
- 蛋白名称：
- Troponin I cardiac muscle
- 免疫原：
- The antiserum was produced against synthesized peptide derived from mouse TNNI3. AA range:5-54
- 特异性：
- Troponin I-C Polyclonal Antibody detects endogenous levels of Troponin I-C protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- TNNI3;TNNC1;Troponin I; cardiac muscle;Cardiac troponin I
- 背景：
- Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
