TRH-R1 Polyclonal Antibody

    • 货号:YT4734
    • 应用:WB;IF;ELISA
    • 种属:Human;Mouse;Rat;Monkey
      • 靶点:
      • TRH-R1
      • 简介:
      • >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction
      • 基因名称:
      • TRHR
      • 蛋白名称:
      • Thyrotropin-releasing hormone receptor
      • Human Gene Id:
      • 7201
      • Human Swiss Prot No:
      • P34981
      • Mouse Swiss Prot No:
      • P21761
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human TRHR. AA range:195-244
      • 特异性:
      • TRH-R1 Polyclonal Antibody detects endogenous levels of TRH-R1 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • TRHR;Thyrotropin-releasing hormone receptor;TRH-R;Thyroliberin receptor
      • 实测条带:
      • 50kD
      • 背景:
      • This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011],
      • 功能:
      • function:Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
      • 细胞定位:
      • Cell membrane ; Multi-pass membrane protein .
      • 组织表达:
      • Brain,Pituitary,Placenta,
      • 产品图片
      • Immunofluorescence analysis of A549 cells, using TRHR Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from COS7 cells, using TRHR Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HepG2 cells using TRHR antibody.