• 靶点：
• TNF-IP 8L2

• 基因名称：
• TNFAIP8L2

• 蛋白名称：
• Tumor necrosis factor alpha-induced protein 8-like protein 2

• Human Gene Id：
• 79626

• Human Swiss Prot No：
• Q6P589

• Mouse Gene Id：
• 69769

• Mouse Swiss Prot No：
• Q9D8Y7

• Rat Gene Id：
• 310663

• Rat Swiss Prot No：
• Q6AYJ8

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human TNFAIP8L2. AA range:11-60

• 特异性：
• TNF-IP 8L2 Polyclonal Antibody detects endogenous levels of TNF-IP 8L2 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• TNFAIP8L2;Tumor necrosis factor alpha-induced protein 8-like protein 2;TIPE2;TNF alpha-induced protein 8-like protein 2;TNFAIP8-like protein 2;Inflammation factor protein 20

• 实测条带：
• 20kD

• 背景：
• domain:The central region was initially thought to constitute a DED (death effector) domain. However, 3D-structure data reveal a previously uncharacterized fold that is different from the predicted fold of a DED (death effector) domain. It consists of a large, hydrophobic central cavity that is poised for cofactor binding.,function:Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.,similarity:Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.,subunit:May interact with CASP8; however, such result is unclear since PubMed:19079267 could not reproduce the interaction with CASP8.,

• 功能：
• domain:The central region was initially thought to constitute a DED (death effector) domain. However, 3D-structure data reveal a previously uncharacterized fold that is different from the predicted fold of a DED (death effector) domain. It consists of a large, hydrophobic central cavity that is poised for cofactor binding.,function:Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.,similarity:Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.,subunit:May interact with CASP8; however, such result is unclear since PubMed:19079267 could not reproduce the interaction with CASP8.,

• 细胞定位：
• cytoplasm,

• 组织表达：
• Lymph node,Pancreas,Small intestine,

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