TDAG51 Polyclonal Antibody
- 货号：YT4590
- 应用：WB;ELISA
- 种属：Human;Mouse;Rat
- 蛋白名称：
- Pleckstrin homology-like domain family A member 1
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human PHLA1. AA range:271-320
- 特异性：
- TDAG51 Polyclonal Antibody detects endogenous levels of TDAG51 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- PHLDA1;PHRIP;TDAG51;Pleckstrin homology-like domain family A member 1;Apoptosis-associated nuclear protein;Proline- and glutamine-rich protein;PQ-rich protein;PQR protein;Proline- and histidine-rich protein;T-cell death-associated
- 背景：
- This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008],
- 功能：
- function:Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.,induction:Induced by homocysteine and other ER stress-inducing reagents. Induced by phorbolester (TPA)/ionomycin, and stimulation of the T-cell receptor (TCR) complex in T-cells.,similarity:Contains 1 PH domain.,subcellular location:Colocalizes with intracellular vesicles.,subunit:Interacts with RPL14, EIF3S7 and PABPC4.,tissue specificity:Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).,
- 细胞定位：
- Cytoplasm . Cytoplasmic vesicle . Nucleus, nucleolus . Colocalizes with intracellular vesicles. .
- 组织表达：
- Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).
- Western Blot analysis of RAW264.7 cells using TDAG51 Polyclonal Antibody
- Western blot analysis of lysates from RAW264.7 cells, using PHLA1 Antibody. The lane on the right is blocked with the synthesized peptide.
