TCP-1 θ Polyclonal Antibody
- 货号：YT4587
- 应用：WB;ELISA
- 种属：Human;Mouse
- 蛋白名称：
- T-complex protein 1 subunit theta
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human CCT8. AA range:361-410
- 特异性：
- TCP-1 θ Polyclonal Antibody detects endogenous levels of TCP-1 θ protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- CCT8;C21orf112;CCTQ;KIAA0002;T-complex protein 1 subunit theta;TCP-1-theta;CCT-theta;Renal carcinoma antigen NY-REN-15
- 背景：
- This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013],
- 功能：
- function:Molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.,
- 细胞定位：
- Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body .
- 组织表达：
- Adipose tissue,B-cell lymphoma,Bone marrow,Chondrosarcoma,Epitheliu
- Western Blot analysis of HeLa cells using TCP-1 θ Polyclonal Antibody
- Western blot analysis of CCT8 Antibody. The lane on the right is blocked with the CCT8 peptide.
- Western blot analysis of the lysates from HeLa cells using CCT8 antibody.
