T2R45 Polyclonal Antibody
- 货号：YT4511
- 应用：WB;ELISA
- 种属：Human
- 蛋白名称：
- Taste receptor type 2 member 45
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human TAS2R45. AA range:221-270
- 特异性：
- T2R45 Polyclonal Antibody detects endogenous levels of T2R45 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- TAS2R45;GPR59;Taste receptor type 2 member 45;T2R45;G-protein coupled receptor 59
- 背景：
- function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,
- 功能：
- function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,
- 细胞定位：
- Membrane; Multi-pass membrane protein.
- 组织表达：
- Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
- Western blot analysis of TAS2R45 Antibody. The lane on the right is blocked with the TAS2R45 peptide.
- Western blot analysis of the lysates from HepG2 cells using TAS2R45 antibody.
