• 靶点：
• SSBP1

• 简介：
• >>DNA replication;>>Mismatch repair;>>Homologous recombination

• 基因名称：
• SSBP1

• 蛋白名称：
• Single-stranded DNA-binding protein mitochondrial

• Human Gene Id：
• 6742

• Human Swiss Prot No：
• Q04837

• Mouse Gene Id：
• 381760

• Mouse Swiss Prot No：
• Q9CYR0

• Rat Gene Id：
• 54304

• Rat Swiss Prot No：
• P28042

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human MtSSB. AA range:99-148

• 特异性：
• SSBP1 Polyclonal Antibody detects endogenous levels of SSBP1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SSBP1;SSBP;Single-stranded DNA-binding protein; mitochondrial;Mt-SSB;MtSSB;PWP1-interacting protein 17

• 实测条带：
• 17kD

• 背景：
• SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010],

• 功能：
• function:This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 SSB domain.,subunit:Homotetramer.,

• 细胞定位：
• Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid .

• 组织表达：
• Expressed in retinal ganglion cells, photoreceptors, pigmented epithelium and fibroblasts (at protein level).

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