Sideroflexin-4 Polyclonal Antibody
- 货号:YT4298
- 应用:WB;IHC
- 种属:Human
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human SFXN4. AA range:1-50
- 特异性:
- Sideroflexin-4 Polyclonal Antibody detects endogenous levels of Sideroflexin-4 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000;IHC 1:50-300
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- SFXN4;BCRM1;Sideroflexin-4;Breast cancer resistance marker 1
- 背景:
- This gene encodes a member of the sideroflexin family. The encoded protein is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene. [provided by RefSeq, Jan 2014],
- 功能:
- function:Potential iron transporter.,similarity:Belongs to the sideroflexin family.,
- 细胞定位:
- Mitochondrion inner membrane ; Multi-pass membrane protein .
- 组织表达:
- Mammary tumor,Placenta,Tongue,
- Western Blot analysis of various cells using Sideroflexin-4 Polyclonal Antibody
- Western blot analysis of lysates from HUVEC cells, using SFXN4 Antibody. The lane on the right is blocked with the synthesized peptide.
- Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).