SERGEF Polyclonal Antibody

    • 货号:YT4254
    • 应用:WB;ELISA;IHC
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • SERGEF
      • 基因名称:
      • SERGEF
      • 蛋白名称:
      • Secretion-regulating guanine nucleotide exchange factor
      • Human Swiss Prot No:
      • Q9UGK8
      • Mouse Swiss Prot No:
      • Q80YD6
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228
      • 特异性:
      • SERGEF Polyclonal Antibody detects endogenous levels of SERGEF protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • SERGEF;DELGEF;GNEFR;Secretion-regulating guanine nucleotide exchange factor;Deafness locus-associated putative guanine nucleotide exchange factor;DelGEF;Guanine nucleotide exchange factor-related protein
      • 实测条带:
      • 50kD
      • 背景:
      • function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,
      • 功能:
      • function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,
      • 细胞定位:
      • Cytoplasm . Nucleus .
      • 组织表达:
      • Fetal brain,Ovary,
      • 产品图片
      • Western blot analysis of SERGEF Antibody. The lane on the right is blocked with the SERGEF peptide.
      • Western blot analysis of the lysates from HT-29 cells using SERGEF antibody.
      • Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).