SENP8 Polyclonal Antibody
- 货号:YT4242
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse;Rat
- 蛋白名称:
- Sentrin-specific protease 8
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human SENP8. AA range:161-210
- 特异性:
- SENP8 Polyclonal Antibody detects endogenous levels of SENP8 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- SENP8;DEN1;NEDP1;PRSC2;FKSG8;Sentrin-specific protease 8;Deneddylase-1;NEDD8-specific protease 1;Protease; cysteine 2;Sentrin/SUMO-specific protease SENP8
- 背景:
- This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],
- 功能:
- function:Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.,similarity:Belongs to the peptidase C48 family.,tissue specificity:Broadly expressed, with highest levels in kidney and pancreas.,
- 组织表达:
- Broadly expressed, with highest levels in kidney and pancreas.
- Western Blot analysis of various cells using SENP8 Polyclonal Antibody
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP8 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from HUVEC cells, using SENP8 Antibody. The lane on the right is blocked with the synthesized peptide.