• 靶点：
• Sec23B

• 简介：
• >>Protein processing in endoplasmic reticulum

• 基因名称：
• SEC23B

• 蛋白名称：
• Protein transport protein Sec23B

• Human Gene Id：
• 10483

• Human Swiss Prot No：
• Q15437

• Mouse Gene Id：
• 27054

• Mouse Swiss Prot No：
• Q9D662

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human Sec23B. AA range:495-544

• 特异性：
• Sec23B Polyclonal Antibody detects endogenous levels of Sec23B protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SEC23B;Protein transport protein Sec23B;SEC23-related protein B

• 实测条带：
• 86kD

• 背景：
• The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010],

• 功能：
• function:Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.,similarity:Belongs to the SEC23/SEC24 family. SEC23 subfamily.,subunit:COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1.,

• 细胞定位：
• Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol .

• 组织表达：
• Ubiquitously expressed.

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