• 靶点：
• RhoBTB1/2

• 简介：
• >>Ubiquitin mediated proteolysis

• 基因名称：
• RHOBTB1/RHOBTB2

• 蛋白名称：
• Rho-related BTB domain-containing protein 1/2

• Human Gene Id：
• 23221/9886

• Human Swiss Prot No：
• O94844/Q9BYZ6

• Mouse Gene Id：
• 69288/246710

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human RHBT2. AA range:61-110

• 特异性：
• RhoBTB1/2 Polyclonal Antibody detects endogenous levels of RhoBTB1/2 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• RHOBTB1;KIAA0740;Rho-related BTB domain-containing protein 1;RHOBTB2;DBC2;KIAA0717;Rho-related BTB domain-containing protein 2;Deleted in breast cancer 2 gene protein;p83

• 实测条带：
• 83kD

• 背景：
• The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],

• 功能：
• similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.,

• 细胞定位：
• intracellular,cytosol,plasma membrane,

• 组织表达：
• Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.

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