Relaxin Receptor 3 Polyclonal Antibody
- 货号：YT4043
- 应用：WB;IHC
- 种属：Human;Mouse;Rat
- 简介：
- >>Neuroactive ligand-receptor interaction;>>Relaxin signaling pathway
- 蛋白名称：
- Relaxin-3 receptor 1
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human RXFP3. AA range:161-210
- 特异性：
- Relaxin Receptor 3 Polyclonal Antibody detects endogenous levels of Relaxin Receptor 3 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000;IHC 1:50-300
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- RXFP3;RLN3R1;SALPR;Relaxin-3 receptor 1;RLN3 receptor 1;G protein-coupled receptor SALPR;G-protein coupled receptor GPCR135;Relaxin family peptide receptor 3;Somatostatin- and angiotensin-like peptide receptor
- 背景：
- function:Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.,
- 功能：
- function:Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.,
- 细胞定位：
- Cell membrane; Multi-pass membrane protein.
- 组织表达：
- Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
- Western blot analysis of lysates from K562 cells, using RXFP3 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from Jurkat cells using RXFP3 antibody.
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
