• 靶点：
• RASSF4

• 简介：
• >>Hippo signaling pathway - multiple species

• 基因名称：
• RASSF4

• 蛋白名称：
• Ras association domain-containing protein 4

• Human Gene Id：
• 83937

• Human Swiss Prot No：
• Q9H2L5

• Mouse Swiss Prot No：
• Q8CB96

• Rat Gene Id：
• 362423

• Rat Swiss Prot No：
• Q566C5

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human RASSF4. AA range:134-183

• 特异性：
• RASSF4 Polyclonal Antibody detects endogenous levels of RASSF4 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• RASSF4;AD037;Ras association domain-containing protein 4

• 实测条带：
• 37kD

• 背景：
• The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. [provided by RefSeq, Jul 2008],

• 功能：
• function:Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subunit:Interacts directly with activated KRAS in a GTP-dependent manner.,tissue specificity:Widely expressed. Frequently down-regulated in tumor cell lines.,

• 组织表达：
• Widely expressed. Frequently down-regulated in tumor cell lines.

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