Ran BP-17 Polyclonal Antibody
- 货号：YT3999
- 应用：WB;IHC
- 种属：Human;Mouse
- 简介：
- >>Nucleocytoplasmic transport
- 蛋白名称：
- Ran-binding protein 17
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human RANBP17. AA range:145-194
- 特异性：
- Ran BP-17 Polyclonal Antibody detects endogenous levels of Ran BP-17 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000;IHC 1:50-300
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- RANBP17;Ran-binding protein 17
- 背景：
- RAN binding protein 17(RANBP17) Homo sapiens The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002],
- 功能：
- function:May function as a nuclear transport receptor.,similarity:Belongs to the exportin family.,subunit:Binds to nucleoporins and the GTP-bound form of Ran.,tissue specificity:Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.,
- 细胞定位：
- Cytoplasm . Nucleus . Nucleus, nuclear pore complex .
- 组织表达：
- Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.
- Western blot analysis of RANBP17 Antibody. The lane on the right is blocked with the RANBP17 peptide.
- Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
