Rab 7L1 Polyclonal Antibody

    • 货号:YT3939
    • 应用:WB;ELISA;IHC
    • 种属:Human;Mouse;Rat
      • 靶点:
      • Rab 7L1
      • 基因名称:
      • RAB7L1
      • 蛋白名称:
      • Ras-related protein Rab-7L1
      • Human Gene Id:
      • 8934
      • Human Swiss Prot No:
      • O14966
      • Mouse Swiss Prot No:
      • Q91YQ1
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human RAB7L1. AA range:115-164
      • 特异性:
      • Rab 7L1 Polyclonal Antibody detects endogenous levels of Rab 7L1 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • RAB7L1;Ras-related protein Rab-7L1;Rab-7-like protein 1
      • 实测条带:
      • 28kD
      • 背景:
      • similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
      • 功能:
      • similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
      • 细胞定位:
      • Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus . Golgi apparatus, trans-Golgi network . Vacuole . Cytoplasm, cytoskeleton . Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (PubMed:29212815). Colocalizes with GM130 at the Golgi apparatus (PubMed:22042847). Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus (PubMed:22042847). Colocalizes with TGN46 at the trans-Golgi network (TGN) (PubMed:24788816). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery (PubMed:22042847). .
      • 组织表达:
      • Ubiquitous.
      • 产品图片
      • Western Blot analysis of various cells using Rab 7L1 Polyclonal Antibody
      • Western blot analysis of lysates from HT-29 cells, using RAB7L1 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HepG2 cells using RAB7L1 antibody.
      • Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).