PMS2/PMS2CL Polyclonal Antibody

    • 货号:YT3805
    • 应用:IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • PMS2/PMS2CL
      • 基因名称:
      • PMS2/PMS2CL
      • 蛋白名称:
      • Mismatch repair endonuclease PMS2/Protein PMS2CL
      • Human Gene Id:
      • 5395
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174
      • 特异性:
      • PMS2/PMS2CL Polyclonal Antibody detects endogenous levels of PMS2/PMS2CL protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • PMS2CL;Protein PMS2CL;PMS2-C terminal-like protein;PMS2;PMSL2;Mismatch repair endonuclease PMS2;DNA mismatch repair protein PMS2;PMS1 protein homolog 2
      • 分子量:
      • 21kD
      • 背景:
      • caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
      • 功能:
      • caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
      • 细胞定位:
      • mismatch repair complex,
      • 组织表达:
      • Fetal brain,Testis,
      • 产品图片
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PMS2/PMS2CL Antibody. The picture on the right is blocked with the synthesized peptide.