PMS2/PMS2CL Polyclonal Antibody
- 货号:YT3805
- 应用:IHC;IF;ELISA
- 种属:Human;Rat;Mouse;
- 蛋白名称:
- Mismatch repair endonuclease PMS2/Protein PMS2CL
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174
- 特异性:
- PMS2/PMS2CL Polyclonal Antibody detects endogenous levels of PMS2/PMS2CL protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- PMS2CL;Protein PMS2CL;PMS2-C terminal-like protein;PMS2;PMSL2;Mismatch repair endonuclease PMS2;DNA mismatch repair protein PMS2;PMS1 protein homolog 2
- 背景:
- caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
- 功能:
- caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
- 细胞定位:
- mismatch repair complex,
- 组织表达:
- Fetal brain,Testis,
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PMS2/PMS2CL Antibody. The picture on the right is blocked with the synthesized peptide.