• 靶点：
• PIG-H

• 简介：
• >>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;>>Metabolic pathways

• 基因名称：
• PIGH

• 蛋白名称：
• Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

• Human Gene Id：
• 5283

• Human Swiss Prot No：
• Q14442

• Mouse Gene Id：
• 110417

• Mouse Swiss Prot No：
• Q5M9N4

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human PIGH. AA range:137-186

• 特异性：
• PIG-H Polyclonal Antibody detects endogenous levels of PIG-H protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• PIGH;Phosphatidylinositol N-acetylglucosaminyltransferase subunit H;Phosphatidylinositol-glycan biosynthesis class H protein;PIG-H

• 分子量：
• 21kD

• 背景：
• This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008],

• 功能：
• catalytic activity:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.,function:Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.,online information:Phosphatidylinositol N-acetylglucosaminyltransferase subunit H,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGH family.,subunit:Associates with PIGA, PIGC, PIGP, PIGQ and DPM2. The latter is not essential for activity.,

• 细胞定位：
• Cytoplasm.

• 组织表达：
• Blood,Lung,Placenta,

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