• 靶点：
• PABP3

• 简介：
• >>mRNA surveillance pathway;>>RNA degradation

• 基因名称：
• PABPC3

• 蛋白名称：
• Polyadenylate-binding protein 3

• Human Gene Id：
• 5042

• Human Swiss Prot No：
• Q9H361

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human PABPC3. AA range:352-401

• 特异性：
• PABP3 Polyclonal Antibody detects endogenous levels of PABP3 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000.IHC:1:50-300 ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• PABPC3;PABP3;PABPL3;Polyadenylate-binding protein 3;PABP-3;Poly(A)-binding protein 3;Testis-specific poly(A)-binding protein

• 实测条带：
• 70kD

• 背景：
• Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002],

• 功能：
• function:Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.,similarity:Belongs to the polyadenylate-binding protein type-1 family.,similarity:Contains 1 PABC domain.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Testis specific.,

• 细胞定位：
• Cytoplasm .

• 组织表达：
• Testis specific.

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