p70 S6 kinase β Polyclonal Antibody
- 货号：YT3559
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Mouse
- 简介：
- >>EGFR tyrosine kinase inhibitor resistance;>>Endocrine resistance;>>ErbB signaling pathway;>>HIF-1 signaling pathway;>>Autophagy - animal;>>mTOR signaling pathway;>>PI3K-Akt signaling pathway;>>AMPK signaling pathway;>>Longevity regulating pathway;>>Longevity regulating pathway - multiple species;>>TGF-beta signaling pathway;>>Apelin signaling pathway;>>Fc gamma R-mediated phagocytosis;>>Thermogenesis;>>Insulin signaling pathway;>>Insulin resistance;>>Shigellosis;>>Human cytomegalovirus infection;>>Human papillomavirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>Chemical carcinogenesis - receptor activation;>>Colorectal cancer;>>Pancreatic cancer;>>Acute myeloid leukemia;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer;>>Choline metabolism in cancer;>>PD-L1 expression and PD-1 checkpoint pathway in cancer
- 蛋白名称：
- Ribosomal protein S6 kinase beta-2
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase beta. AA range:389-438
- 特异性：
- p70 S6 kinase β Polyclonal Antibody detects endogenous levels of p70 S6 kinase β protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- RPS6KB2;STK14B;Ribosomal protein S6 kinase beta-2;S6K-beta-2;S6K2;70 kDa ribosomal protein S6 kinase 2;P70S6K2;p70-S6K 2;S6 kinase-related kinase;SRK;Serine/threonine-protein kinase 14B;p70 ribosomal S6 kinase beta;S6K-beta;p70
- 背景：
- ribosomal protein S6 kinase B2(RPS6KB2) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015],
- 功能：
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates specifically ribosomal protein S6.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,
- 细胞定位：
- Cytoplasm. Nucleus.
- 组织表达：
- Brain,Epithelium,Lymph,
- Western Blot analysis of various cells using p70 S6 kinase β Polyclonal Antibody
.jpg)
- Western Blot analysis of 293 cells using p70 S6 kinase β Polyclonal Antibody
- Western blot analysis of lysates from 293 cells, using p70 S6 Kinase beta Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HUVECcells using p70 S6 Kinase β antibody.
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
