• 靶点：
• OATP1

• 简介：
• >>Bile secretion

• 基因名称：
• SLCO1A2

• 蛋白名称：
• Solute carrier organic anion transporter family member 1A2

• Human Gene Id：
• 6579

• Human Swiss Prot No：
• P46721

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human SLCO1A2. AA range:251-300

• 特异性：
• OATP1 Polyclonal Antibody detects endogenous levels of OATP1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SLCO1A2;OATP;OATP1;OATP1A2;SLC21A3;Solute carrier organic anion transporter family member 1A2;OATP-A;Organic anion-transporting polypeptide 1;OATP-1;Sodium-independent organic anion transporter;Solute carrier family 21 member 3

• 实测条带：
• 80kD

• 背景：
• This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008],

• 功能：
• function:Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids.,similarity:Belongs to the organo anion transporter (TC 2.A.60) family.,

• 细胞定位：
• Cell membrane; Multi-pass membrane protein.

• 组织表达：
• Brain,Liver,Teratocarcinoma,

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