NT5C1A Polyclonal Antibody

    • 货号:YT3198
    • 应用:WB;IF;ELISA
    • 种属:Human;Mouse
      • 靶点:
      • NT5C1A
      • 简介:
      • >>Purine metabolism;>>Pyrimidine metabolism;>>Nicotinate and nicotinamide metabolism;>>Metabolic pathways;>>Nucleotide metabolism
      • 基因名称:
      • NT5C1A
      • 蛋白名称:
      • Cytosolic 5'-nucleotidase 1A
      • Human Swiss Prot No:
      • Q9BXI3
      • Mouse Swiss Prot No:
      • A3KFX0
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human NT5C1A. AA range:151-200
      • 特异性:
      • NT5C1A Polyclonal Antibody detects endogenous levels of NT5C1A protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • NT5C1A;Cytosolic 5'-nucleotidase 1A;cN1A;Cytosolic 5'-nucleotidase IA;cN-I;cN-IA
      • 实测条带:
      • 41kD
      • 背景:
      • Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008],
      • 功能:
      • catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.,similarity:Belongs to the 5'-nucleotidase type 3 family.,tissue specificity:Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.,
      • 细胞定位:
      • Cytoplasm.
      • 组织表达:
      • Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.
      • 产品图片
      • Immunofluorescence analysis of A549 cells, using NT5C1A Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from MCF-7 and HepG2 cells, using NT5C1A Antibody. The lane on the right is blocked with the synthesized peptide.