NT-4 Polyclonal Antibody

    • 货号:YT3197
    • 应用:IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • NT-4
      • 简介:
      • >>MAPK signaling pathway;>>Ras signaling pathway;>>PI3K-Akt signaling pathway;>>Neurotrophin signaling pathway
      • 基因名称:
      • NTF4
      • 蛋白名称:
      • Neurotrophin-4
      • Human Gene Id:
      • 4909
      • Human Swiss Prot No:
      • P34130
      • Mouse Swiss Prot No:
      • Q80VU4
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human NT-4. AA range:71-120
      • 特异性:
      • NT-4 Polyclonal Antibody detects endogenous levels of NT-4 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • NTF4;NTF5;Neurotrophin-4;NT-4;Neurotrophin-5;NT-5;Neutrophic factor 4
      • 分子量:
      • 22kD
      • 背景:
      • This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008],
      • 功能:
      • function:Target-derived survival factor for peripheral sensory sympathetic neurons.,similarity:Belongs to the NGF-beta family.,tissue specificity:Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.,
      • 细胞定位:
      • Secreted.
      • 组织表达:
      • Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
      • 产品图片
      • Immunohistochemical analysis of paraffin-embedded Human prostate cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Immunohistochemistry analysis of NT-4 antibody in paraffin-embedded human prostate carcinoma tissue.