• 靶点：
• NRBF-2

• 简介：
• >>Autophagy - animal;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases

• 基因名称：
• NRBF2

• 蛋白名称：
• Nuclear receptor-binding factor 2

• Human Gene Id：
• 29982

• Human Swiss Prot No：
• Q96F24

• Mouse Gene Id：
• 641340

• Mouse Swiss Prot No：
• Q8VCQ3

• Rat Gene Id：
• 58839

• Rat Swiss Prot No：
• Q9QYK3

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human NRBF2. AA range:140-189

• 特异性：
• NRBF-2 Polyclonal Antibody detects endogenous levels of NRBF-2 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• NRBF2;COPR;Nuclear receptor-binding factor 2;NRBF-2;Comodulator of PPAR and RXR

• 实测条带：
• 36kD

• 背景：
• function:May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).,subunit:Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand.,tissue specificity:Detected in keratinocytes, liver and placenta.,

• 功能：
• function:May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).,subunit:Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand.,tissue specificity:Detected in keratinocytes, liver and placenta.,

• 细胞定位：
• Nucleus . Cytoplasm . Cytoplasmic vesicle . Cytoplasmic vesicle, autophagosome .

• 组织表达：
• Detected in keratinocytes, liver and placenta (PubMed:15610520). Expressed in a subset of cells in pediatric medulloblastoma (PubMed:18619852).

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