NK-TR Polyclonal Antibody
- 货号:YT3137
- 应用:IHC;IF;WB;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- NK-tumor recognition protein
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human NKTR. AA range:784-833
- 特异性:
- NK-TR Polyclonal Antibody detects endogenous levels of NK-TR protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- NKTR;NK-tumor recognition protein;NK-TR protein;Natural-killer cells cyclophilin-related protein
- 背景:
- This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008],
- 功能:
- catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:Component of a putative tumor-recognition complex. Involved in the function of NK cells.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Attached to the membrane via its N-terminus.,
- 组织表达:
- Aorta endothelial cell,Blood,Epithelium,Fetal kidney,Human endometr
- Immunofluorescence analysis of HeLa cells, using NKTR Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NKTR Antibody. The picture on the right is blocked with the synthesized peptide.