NKp46 Polyclonal Antibody
- 货号：YT3136
- 应用：WB;ELISA
- 种属：Human;Rat;Mouse;
- 简介：
- >>Natural killer cell mediated cytotoxicity
- 蛋白名称：
- Natural cytotoxicity triggering receptor 1
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194
- 特异性：
- NKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- NCR1;LY94;Natural cytotoxicity triggering receptor 1;Lymphocyte antigen 94 homolog;NK cell-activating receptor;Natural killer cell p46-related protein;NK-p46;NKp46;hNKp46;CD antigen CD335
- 背景：
- function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,
- 功能：
- function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,
- 细胞定位：
- Cell membrane ; Single-pass type I membrane protein .
- 组织表达：
- Selectively expressed by both resting and activated NK cells.
- Western Blot analysis of various cells using NKp46 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
- Western blot analysis of lysates from 293, HepG2, MCF-7, and A549 cells, using NCR1 Antibody. The lane on the right is blocked with the synthesized peptide.
