NKIAMRE Polyclonal Antibody
- 货号：YT3134
- 应用：IHC;IF;WB;ELISA
- 种属：Human;Rat;Mouse;
- 蛋白名称：
- Cyclin-dependent kinase-like 3
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human CDKL3. AA range:291-340
- 特异性：
- NKIAMRE Polyclonal Antibody detects endogenous levels of NKIAMRE protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- CDKL3;NKIAMRE;Cyclin-dependent kinase-like 3;Serine/threonine-protein kinase NKIAMRE
- 背景：
- The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
- 功能：
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,
- 组织表达：
- Fetal heart,Testis,
- Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using CDKL3 Antibody. The picture on the right is blocked with the synthesized peptide.
