NK-3R Polyclonal Antibody
- 货号：YT3133
- 应用：WB;IF;ELISA
- 种属：Human;Mouse;Rat
- 简介：
- >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction
- 蛋白名称：
- Neuromedin-K receptor
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human NK3R. AA range:401-450
- 特异性：
- NK-3R Polyclonal Antibody detects endogenous levels of NK-3R protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- TACR3;NK3R;TAC3R;Neuromedin-K receptor;NKR;NK-3 receptor;NK-3R;Neurokinin B receptor;Tachykinin receptor 3
- 背景：
- This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008],
- 功能：
- function:This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,miscellaneous:The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.,PTM:The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.,similarity:Belongs to the G-protein coupled receptor 1 family.,
- 细胞定位：
- Cell membrane; Multi-pass membrane protein.
- 组织表达：
- Brain,G-protein coupled receptors,PCR rescued clones,Placenta,
- Western Blot analysis of various cells using NK-3R Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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- Western Blot analysis of COLO205 cells using NK-3R Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
- Immunofluorescence analysis of A549 cells, using NK3R Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from COLO205 cells, using NK3R Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HepG2 cells using NK3R antibody.
