Neuron Navigator 2 Polyclonal Antibody

    • 货号:YT3070
    • 应用:IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • Neuron Navigator 2
      • 基因名称:
      • NAV2
      • 蛋白名称:
      • Neuron navigator 2
      • Human Swiss Prot No:
      • Q8IVL1
      • 免疫原:
      • Synthesized peptide derived from Neuron Navigator 2 . at AA range: 2040-2120
      • 特异性:
      • Neuron Navigator 2 Polyclonal Antibody detects endogenous levels of Neuron Navigator 2 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • NAV2;HELAD1;KIAA1419;POMFIL2;RAINB1;STEERIN2;Neuron navigator 2;Helicase APC down-regulated 1;Pore membrane and/or filament-interacting-like protein 2;Retinoic acid inducible in neuroblastoma 1;Steerin-2;Unc-53 homolog 2;unc53H2
      • 分子量:
      • 268kD
      • 背景:
      • This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
      • 功能:
      • alternative products:Additional isoforms may exist,caution:PubMed:15158073 experiments have been carried out in mouse.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,developmental stage:Highly expressed in the nervous system of developing embryos. Also expressed in fetal heart, liver and kidney.,function:Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.,induction:By all-trans retinoic acid (atRA). Up-regulated in colorectal carcinomas.,similarity:Belongs to the Nav/unc-53 family.,similarity:Contains 1 CH (calponin-homology) domain.,tissue specificity:Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expr
      • 细胞定位:
      • Nucleus .
      • 组织表达:
      • Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.
      • 产品图片
      • Immunohistochemical analysis of paraffin-embedded human spleen. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).