Neuron Navigator 1 Polyclonal Antibody
- 货号：YT3069
- 应用：IHC;IF;ELISA
- 种属：Human;Mouse
- 免疫原：
- Synthesized peptide derived from Neuron Navigator 1 . at AA range: 510-590
- 特异性：
- Neuron Navigator 1 Polyclonal Antibody detects endogenous levels of Neuron Navigator 1 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- NAV1;KIAA1151;KIAA1213;POMFIL3;STEERIN1;Neuron navigator 1;Pore membrane and/or filament-interacting-like protein 3;Steerin-1;Unc-53 homolog 1;unc53H1
- 背景：
- This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],
- 功能：
- developmental stage:Expressed in fetal brain and heart.,function:May be involved in neuronal migration.,similarity:Belongs to the Nav/unc-53 family.,subcellular location:Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones.,subunit:Interacts with tubulin.,tissue specificity:Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.,
- 细胞定位：
- Cytoplasm, cytoskeleton . Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity). .
- 组织表达：
- Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
