• 靶点：
• Neuromedin-U

• 简介：
• >>Neuroactive ligand-receptor interaction

• 基因名称：
• NMU

• 蛋白名称：
• Neuromedin-U

• Human Gene Id：
• 10874

• Human Swiss Prot No：
• P48645

• Mouse Swiss Prot No：
• Q9QXK8

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human NMU. AA range:125-174

• 特异性：
• Neuromedin-U Polyclonal Antibody detects endogenous levels of Neuromedin-U protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• NMU;Neuromedin-U

• 实测条带：
• 22kD

• 背景：
• This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015],

• 功能：
• function:Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder.,similarity:Belongs to the NmU family.,tissue specificity:Expressed throughout the enteric nervous system with highest levels being found in the jejunum.,

• 细胞定位：
• Secreted.

• 组织表达：
• Expressed throughout the enteric nervous system with highest levels being found in the jejunum.

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