• 靶点：
• NDUFS6

• 简介：
• >>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy

• 基因名称：
• NDUFS6

• 蛋白名称：
• NADH dehydrogenase [ubiquinone] iron-sulfur protein 6 mitochondrial

• Human Gene Id：
• 4726

• Human Swiss Prot No：
• O75380

• Mouse Gene Id：
• 407785

• Mouse Swiss Prot No：
• P52503

• Rat Gene Id：
• 29478

• Rat Swiss Prot No：
• P52504

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human NDUFS6. AA range:75-124

• 特异性：
• NDUFS6 Polyclonal Antibody detects endogenous levels of NDUFS6 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• NDUFS6;NADH dehydrogenase [ubiquinone] iron-sulfur protein 6; mitochondrial;Complex I-13kD-A;CI-13kD-A;NADH-ubiquinone oxidoreductase 13 kDa-A subunit

• 分子量：
• 14kD

• 背景：
• This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009],

• 功能：
• function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFS6 subunit family.,subunit:Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.,

• 细胞定位：
• Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .

• 组织表达：
• Lung,Skin,

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