NDUFS5 Polyclonal Antibody
- 货号：YT3019
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Rat;Mouse;
- 简介：
- >>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
- 蛋白名称：
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human NDUFS5. AA range:57-106
- 特异性：
- NDUFS5 Polyclonal Antibody detects endogenous levels of NDUFS5 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- NDUFS5;NADH dehydrogenase [ubiquinone] iron-sulfur protein 5;Complex I-15 kDa;CI-15 kDa;NADH-ubiquinone oxidoreductase 15 kDa subunit
- 背景：
- This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17. [provided by RefSeq, May 2010],
- 功能：
- function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFS5 subunit family.,subunit:Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.,
- 细胞定位：
- Mitochondrion inner membrane ; Peripheral membrane protein . Mitochondrion intermembrane space .
- 组织表达：
- Blood vessels- blood vessel,Kidney,Umbilical cord blood,
- Immunohistochemistry analysis of paraffin-embedded human heart, using NDUFS5 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
