NDUFS3 Polyclonal Antibody
- 货号：YT3018
- 应用：WB;ELISA
- 种属：Human;Mouse
- 简介：
- >>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
- 蛋白名称：
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 mitochondrial
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human NDUFS3. AA range:117-166
- 特异性：
- NDUFS3 Polyclonal Antibody detects endogenous levels of NDUFS3 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- NDUFS3;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial;Complex I-30kD;CI-30kD;NADH-ubiquinone oxidoreductase 30 kDa subunit
- 背景：
- This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009],
- 功能：
- catalytic activity:NADH + acceptor = NAD(+) + reduced acceptor.,catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol.,function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I 30 kDa subunit family.,subunit:Mammalian complex I is composed of 45 different subunits.,
- 细胞定位：
- Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
- 组织表达：
- Brain,Cajal-Retzius cell,Pituitary,Skin,Stomach mucosa,Uter
- Western Blot analysis of 293T cells using NDUFS3 Polyclonal Antibody diluted at 1:500
- Western blot analysis of lysates from mouse brain, using NDUFS3 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from COLO205 cells using NDUFS3 antibody.
