NCKX6 Polyclonal Antibody
- 货号:YT2995
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Rat;Mouse;
- 蛋白名称:
- Sodium/potassium/calcium exchanger 6
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human SLC24A6. AA range:494-543
- 特异性:
- NCKX6 Polyclonal Antibody detects endogenous levels of NCKX6 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- SLC24A6;NCKX6;NCLX;Sodium/potassium/calcium exchanger 6;Na(+)/K(+)/Ca(2+)-exchange protein 6;Solute carrier family 24 member 6
- 背景:
- SLC24A6 belongs to a family of potassium-dependent sodium/calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion (Cai and Lytton, 2004 [PubMed 14625281]).[supplied by OMIM, Mar 2008],
- 功能:
- function:Transports Ca(2+) in exchange for either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+).,miscellaneous:Strongly inhibited by zinc.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,
- 细胞定位:
- Mitochondrion inner membrane ; Multi-pass membrane protein .
- 组织表达:
- Present in pancreatic beta-cells (at protein level).
- Western blot analysis of lysates from MCF-7 cells, using SLC24A6 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HeLa cells using SLC24A6 antibody.
- Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).