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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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MYL3 Polyclonal Antibody
- 货号:YT2936
- 应用:WB;ELISA;IHC
- 种属:Human;Rat;Mouse;
- 简介:
- >>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Apelin signaling pathway;>>Hypertrophic cardiomyopathy;>>Dilated cardiomyopathy
- 蛋白名称:
- Myosin light chain 3
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human MYL3. AA range:71-120
- 特异性:
- MYL3 Polyclonal Antibody detects endogenous levels of MYL3 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- MYL3;Myosin light chain 3;Cardiac myosin light chain 1;CMLC1;Myosin light chain 1; slow-twitch muscle B/ventricular isoform;MLC1SB;Ventricular/slow twitch myosin alkali light chain
- 背景:
- MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008],
- 功能:
- disease:Defects in MYL3 are the cause of cardiomyopathy familial hypertrophic type 8 (CMH8) [MIM:608751]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. CMH8 inheritance can be autosomal dominant or recessive.,disease:Defects in MYL3 are the cause of cardiomyopathy hypertrophic with mid-left ventricular chamber type 1 (MVC1) [MIM:608751]. MVC1 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.,function:Regulatory
- 细胞定位:
- cytosol,muscle myosin complex,myosin complex,sarcomere,A band,I band,
- 组织表达:
- Heart,Skeletal muscle,
![](/uploadfiles/PIC/yt2936-wb.jpg)
- Western Blot analysis of various cells using MYL3 Polyclonal Antibody
![](/uploadfiles/PIC/yt2936_pic1016618522.jpg)
- Western blot analysis of the lysates from HeLa cells using MYL3 antibody.
![](/uploadfiles/PIC/28weixianaicc.jpg)
- Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).