MIC2 Polyclonal Antibody

    • 货号:YT2758
    • 应用:IF;IHC;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • CD99
      • 简介:
      • >>Cell adhesion molecules;>>Leukocyte transendothelial migration
      • 基因名称:
      • CD99
      • 蛋白名称:
      • CD99 antigen
      • Human Gene Id:
      • 4267
      • Human Swiss Prot No:
      • P14209
      • Mouse Swiss Prot No:
      • Q8VCN6
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human CD99. AA range:11-60
      • 特异性:
      • MIC2 Polyclonal Antibody detects endogenous levels of MIC2 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • CD99;MIC2;MIC2X;MIC2Y;CD99 antigen;12E7;E2 antigen;Protein MIC2;T-cell surface glycoprotein E2;CD antigen CD99
      • 分子量:
      • 19kD
      • 背景:
      • The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016],
      • 功能:
      • function:Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,PTM:Extensively O-glycosylated.,similarity:Belongs to the CD99 family.,
      • 细胞定位:
      • Membrane ; Single-pass type I membrane protein .
      • 组织表达:
      • Brain,Kidney,Skin,T-cell,Uterus,
      • 产品图片
      • Immunofluorescence analysis of COS7 cells, using CD99 Antibody. The picture on the right is blocked with the synthesized peptide.