• 靶点：
• MC5-R

• 简介：
• >>Neuroactive ligand-receptor interaction

• 基因名称：
• MC5R

• 蛋白名称：
• Melanocortin receptor 5

• Human Gene Id：
• 4161

• Human Swiss Prot No：
• P33032

• Mouse Swiss Prot No：
• P41149

• Rat Gene Id：
• 25726

• Rat Swiss Prot No：
• P35345

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human MC5R. AA range:271-320

• 特异性：
• MC5-R Polyclonal Antibody detects endogenous levels of MC5-R protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• MC5R;Melanocortin receptor 5;MC5-R;MC-2

• 实测条带：
• 40kD

• 背景：
• This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010],

• 功能：
• function:Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.,online information:Melanocortin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in the brain but not in the melanoma cells.,

• 细胞定位：
• Cell membrane; Multi-pass membrane protein.

• 组织表达：
• Expressed in the brain but not in the melanoma cells.

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