MAGE-9 Polyclonal Antibody
- 货号：YT2624
- 应用：IHC;IF;ELISA
- 种属：Human;Rat;Mouse;
- 蛋白名称：
- Melanoma-associated antigen 9
- 免疫原：
- Synthesized peptide derived from MAGE-9 . at AA range: 1-80
- 特异性：
- MAGE-9 Polyclonal Antibody detects endogenous levels of MAGE-9 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- MAGEA9;MAGE9;MAGEA9A;MAGEA9B;Melanoma-associated antigen 9;Cancer/testis antigen 1.9;CT1.9;MAGE-9 antigen
- 背景：
- This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008],
- 功能：
- function:Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.,similarity:Contains 1 MAGE domain.,tissue specificity:Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.,
- 组织表达：
- Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
