• 靶点：
• L-type Ca++ CP γ7

• 简介：
• >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy

• 基因名称：
• CACNG7

• 蛋白名称：
• Voltage-dependent calcium channel gamma-7 subunit

• Human Gene Id：
• 59284

• Human Swiss Prot No：
• P62955

• Mouse Gene Id：
• 81904

• Mouse Swiss Prot No：
• P62956

• Rat Gene Id：
• 140728

• Rat Swiss Prot No：
• P62957

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CACNG7. AA range:198-247

• 特异性：
• L-type Ca++ CP γ7 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ7 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CACNG7;Voltage-dependent calcium channel gamma-7 subunit;Neuronal voltage-gated calcium channel gamma-7 subunit;Transmembrane AMPAR regulatory protein gamma-7;TARP gamma-7

• 实测条带：
• 40kD

• 背景：
• calcium voltage-gated channel auxiliary subunit gamma 7(CACNG7) Homo sapiens The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010],

• 功能：
• function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,tissue specificity:Widely expressed.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein .

• 组织表达：
• Detected in heart left ventricle (PubMed:21127204). Widely expressed.

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