• 靶点：
• LHX1

• 基因名称：
• LHX1

• 蛋白名称：
• LIM/homeobox protein Lhx1

• Human Gene Id：
• 3975

• Human Swiss Prot No：
• P48742

• Mouse Gene Id：
• 16869

• Mouse Swiss Prot No：
• P63006

• Rat Gene Id：
• 257634

• Rat Swiss Prot No：
• P63007

• 免疫原：
• Synthesized peptide derived from the Internal region of human LHX1.

• 特异性：
• LHX1 Polyclonal Antibody detects endogenous levels of LHX1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• LHX1;LIM-1;LIM1;LIM/homeobox protein Lhx1;LIM homeobox protein 1;Homeobox protein Lim-1;hLim-1

• 实测条带：
• 44kD

• 背景：
• This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. [provided by RefSeq, Dec 2010],

• 功能：
• domain:The LIM domains exert a negative regulatory function and disruption of the LIM domains produces an activated form. In addition, two activation domains and a negative regulatory domain exist C-terminally to the homeobox.,function:Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,subunit:Interacts with LDB1 via the tandem LIM domains.,tissue specificity:Expressed in the brain, thymus, and tonsils. Expressed in samples from patients with chronic myeloid leukemia (CML) and in 58% of acute myeloid leukemia (AML) cell lines.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Expressed in the brain, thymus, and tonsils. Expressed in samples from patients with chronic myeloid leukemia (CML) and in 58% of acute myeloid leukemia (AML) cell lines.

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