• 靶点：
• IL-20Rα

• 简介：
• >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>JAK-STAT signaling pathway

• 基因名称：
• IL20RA

• 蛋白名称：
• Interleukin-20 receptor subunit alpha

• Human Gene Id：
• 53832

• Human Swiss Prot No：
• Q9UHF4

• Mouse Swiss Prot No：
• Q6PHB0

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human IL-20Ralpha. AA range:173-222

• 特异性：
• IL-20Rα Polyclonal Antibody detects endogenous levels of IL-20Rα protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• IL20RA;Interleukin-20 receptor subunit alpha;IL-20 receptor subunit alpha;IL-20R-alpha;IL-20RA;Cytokine receptor class-II member 8;Cytokine receptor family 2 member 8;CRF2-8;IL-20R1;ZcytoR7

• 实测条带：
• 62kD

• 背景：
• This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

• 功能：
• function:The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.,similarity:Belongs to the type II cytokine receptor family.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer with IL20RB and heterodimer with IL10RB.,tissue specificity:Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.,

• 细胞定位：
• Membrane ; Single-pass type I membrane protein .

• 组织表达：
• Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.

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