• 靶点：
• HSP105

• 简介：
• >>Protein processing in endoplasmic reticulum

• 基因名称：
• HSPH1

• 蛋白名称：
• Heat shock protein 105 kDa

• Human Gene Id：
• 10808

• Human Swiss Prot No：
• Q92598

• Mouse Gene Id：
• 15505

• Mouse Swiss Prot No：
• Q61699

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human HSP105. AA range:791-840

• 特异性：
• HSP105 Polyclonal Antibody detects endogenous levels of HSP105 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• HSPH1;HSP105;HSP110;KIAA0201;Heat shock protein 105 kDa;Antigen NY-CO-25;Heat shock 110 kDa protein

• 实测条带：
• 100kD

• 背景：
• function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,

• 功能：
• function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,

• 细胞定位：
• Cytoplasm .

• 组织表达：
• Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.

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