Hel-N1 Polyclonal Antibody

    • 货号:YT2124
    • 应用:WB;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • Hel-N1
      • 基因名称:
      • ELAVL2
      • 蛋白名称:
      • ELAV-like protein 2
      • Human Gene Id:
      • 1993
      • Human Swiss Prot No:
      • Q12926
      • Mouse Swiss Prot No:
      • Q60899
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human ELAVL2. AA range:11-60
      • 特异性:
      • Hel-N1 Polyclonal Antibody detects endogenous levels of Hel-N1 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • ELAVL2;HUB;ELAV-like protein 2;ELAV-like neuronal protein 1;Hu-antigen B;HuB;Nervous system-specific RNA-binding protein Hel-N1
      • 实测条带:
      • 38kD
      • 背景:
      • ELAV like RNA binding protein 2(ELAVL2) Homo sapiens The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
      • 功能:
      • function:Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.,similarity:Belongs to the RRM elav family.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Brain; neural-specific.,
      • 细胞定位:
      • nucleoplasm,
      • 组织表达:
      • Brain; neural-specific.
      • 产品图片
      • Western Blot analysis of various cells using Hel-N1 Polyclonal Antibody
      • Western blot analysis of lysates from HepG2 and Jurkat cells, using ELAVL2 Antibody. The lane on the right is blocked with the synthesized peptide.